Quick Answer: What Does Zidovudine Treat?

Is zidovudine still used?

Zidovudine, also known as azidothymidine (AZT), was the first antiviral to be approved for the treatment of HIV.

Although no longer a first-line agent, zidovudine is still used in combination with other ARVs for the treatment of HIV [39]..

What are the common adverse effects of zidovudine?

Common side effects of Retrovir include:headache,nausea,vomiting,constipation,trouble sleeping (insomnia),loss of appetite,joint pain, and.changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and trunk).

Is zidovudine an antiviral medication?

Retrovir (zidovudine) is an antiviral medication used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Retrovir is also given during pregnancy to prevent an HIV-infected woman from passing the virus to her baby. Retrovir is not a cure for HIV or AIDS.

Did AZT save lives?

August 17, 1989: The government has announced that 1.4 million healthy, HIV antibody-positive Americans could “benefit” from taking AZT, even though they show no symptoms of disease. New studies have “proven” that AZT is effective in stopping the progression of AIDS in asymptomatic and early ARC cases.

Can you take zidovudine during pregnancy?

This drug should be used during pregnancy only if clearly needed and the benefit outweighs the risk to the fetus. US FDA pregnancy category: Not assigned. Risk summary: Malformative risk with use of this drug in pregnant women is unlikely.

How does the drug zidovudine work?

AZT interferes with an enzyme called reverse transcriptase (RT), which is used by HIV-infected cells to make new viruses. Since AZT inhibits, or reduces the activity of this enzyme, this drug causes HIV-infected cells to produce fewer viruses.

Who should not take zidovudine?

If you experience muscle pain or muscle weakness, call your doctor immediately. Lamivudine and zidovudine may cause life-threatening damage to the liver and a potentially life-threatening condition called lactic acidosis (buildup of lactic acid in the blood). Tell your doctor if you have or have ever had liver disease.

When should I take zidovudine?

Zidovudine comes as a capsule, tablet, and syrup to take by mouth. It is usually taken twice a day by adults and two to three times a day by infants and children. Infants 6 weeks of age and younger may take zidovudine every 6 hours. When zidovudine is taken by pregnant women, it may be taken 5 times a day.

What class of drug is nevirapine?

Nevirapine belongs to a class of drugs known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).

What are the side effect of lamivudine?

Side effects of lamivudine include fatigue, muscle aches, fever and chills, sore throat, nausea, stomach pain or cramps, and diarrhea. Serious side effects are rare, occurring in less than 1% of people taking lamivudine.

What happened to AZT?

What happened after the trial ended suggested something more alarming about AZT. After 16 weeks, one AZT patient was dead, compared to 19 placebo patients; a week later two more patients on AZT had died, compared to four more on the placebo.